Pomegranate ingredients which mimic the Polyphenol ratio of the fruit; potent synergistic effects have been observed in ’natural spectrum’ extracts — particularly pomegranate concentrate normalised to Punicalagins.
J Nutr Biochemistry 2005 (16) 360—367.
Intervention of anti–oxidant system function of aged rats by giving fruit juices with different anti-oxidant capacities.
Xu J, Guo CJ, Yang JJ, Wei JY, Li YF, Pang W, Jiang YG, Cheng S. Dept of Nutrition, Institute of Hygiene & Environmental Medicine, Acedemy of Military Medical Sciences, Tianjin, China.
Determination of Phenolic compounds in pomegranate juice by HPLC.
Artik N, Ceremroglu B, Murakami H, Mori T. Fruit Process. 1998;8:492–499.
抗微生物作用
Punica granatum (Pomegranate) juice provides an HIV-1 entry inhibitor and candidate topical microbicide.
Neurath AR. et al. BMC Infect Dis. 2004 Oct 14;4:41.
神经保护作用
Maternal dietary supplementation with pomegranate juice is neuroprotective in an animal model of neonatal hypoxic-ischemic brain injury.
Loren DJ. et al. Pediatr. Res. 2005 Jun;57(6):858-64. Epub 2005 Mar.
神经保护作用
Inhibitory effect of an Ellagic Acid-rich pomegranate extract on Tyrosinase activity and ultraviolet-induced pigmentation.
Yoshimura M, Watanabe Y, Kasai K, Yamakoshi J, Koga T. Research and Development Division, Kikkoman Corporation.
Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL and platelet aggregation: studies in humans and in atherosclerotic Apolipoprotein E–deficient mice.
Aviram M, Dronfeld L, Rosenblat M, et al. Am J Clin Nutr. 2000;71:1062—1076.
Pomegranate juice flavonoids inhibit low–density lipoprotein oxidation and cardiovascular disease: studies in atherosclerotic mice and in humans.
Aviram M, Dornefeld L, Kaplan M, Gaitini D, Nitecki S, Hofman A, Rosenblat M, Volkova N, Presser D, Attias J, Hayek T, Fuhrman B. Lipid Research Laboratory, Technion Faculty of Medicine, Israel.
伤口治愈
Study on wound healing activity of Punica granatum peel.
Murphy KN. et al., J Med Food. 2004 Summer;7(2):256-9.
伤口治愈
Oxidative stress in arteriogenic erectile dysfunction: prophylactic role of antioxidants.
Azadzoi KM. et al. J Urol. 2005 Jul;174(1):386-93.
皮肤抗老化效果
Pomegranate as a cosmeceutical source: pomegranate fractions promote proliferation and procollagen synthesis and inhibit matrix metalloproteinase-1 production in human skin cells.
Journal of Ethnopharmacology 103: 311-318, 2006.
安全
Repeated oral administration of high doses of the pomegranate ellagitannin punicalagin to rats for 37 days is not toxic.
Cerda B. et al. J Agric Food Chem. 2003 May 21;51(11):3493-501.
Differentiation-promoting activity of pomegranate (punica granatum) fruit extracts in HL-60 human promyelocytic leukemia cells.
Apr 2004, Vol. 7, No. 1: 13-18.
Chemopreventive and adjuvant therapeutic potential of pomegranate (punica granatum) for human breast cancer.
Kim ND, et al. Breast Cancer Res Treat 2002; 71:203-17.
Anthocyanin- and hydrolysable tannin-rich pomegranate fruit extract modulates MAPK and NF-kappaB pathways and inhibits skin tumorigenesis in CD-1 mice.
Afaq F. et al. Int J Cancer 2005 Jan 20;113(3)
生物利用度
Punica granatum (Pomegranate) juice provides an HIV-1 entry inhibitor and candidate topical microbicide.
Neurath AR. et al. BMC Infect Dis. 2004 Oct 14;4:41.
In vitro gastrointestinal digestion study of pomegranate juice phenolic compounds, anthocyanins, and vitaminC.
Perez-Vicente A. et al., J Agric Food Chem. 2002 Apr 10;50(8):2308-12
抗胃溃疡
The inhibition of astric mucosal injury by Punica granatum L. (pomegranate) methanolic extract.
Ajaikumar KB. Et al. J Ethnopharmacol. 2005 Jan 4;96(1-2):171-6.